Home page has to accommodate site hierarchy. The Home page has to give an overview of what the site has to offer - both content (“What can I find here?”) and features (“What can I do here?”) - and how it’s all organized. This is usually handled by the persistent navigation.
Don’t make me think
Being an expert in online usability Krug gathered his experience in a wonderful book. This summary of key thoughts will help you to remember most important principles and laws.