Major Groove — when the backbones of DNA are far apart
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It is not necessary for a man to be actively bad in order to make a failure in life; simple inaction will accomplish it. Nature has everywhere written her protest against idleness; everything which ceases to struggle toward an ideal, the constant effort to get higher and further, which develops manhood and character.
When you're going through something, whether it's a wonderful thing like having a child or a sad thing like losing somebody, you often feel like 'Oh my God, I'm so overwhelmed; I'm dealing with this huge thing on my own.' In fact, poetry's a nice reminder that, no, everybody goes through it. These are universal experiences.