Cancer, like any other illness, is a bore.
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I always like to break out and address the audience. In 'The History Boys', for instance, without any ado, the boys will suddenly turn and talk to the audience and then go back into the action. I find it more adventurous doing it in prose than on the stage, but I like being able to make the reader suddenly sit up.
I can't complain that I've had a public all through my writing life, but people don't quite know what I've written. People don't read you too closely. Perhaps, after I've died, they'll look at my stuff, and read it through, and find there's more in it. That may be wrong, but that's what I comfort myself with.