One of my grandfathers, actually, having gone out there as a minister, decided he would better serve the people as a doctor. So at a very late age - at the age of 38 in fact - he changed course and decided to become a doctor.
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I work with the options I have in front of me and my reasons for choosing a job can vary enormously depending on the circumstances. Sometimes I take a job because it's a group of people I'm dying to work with, and sometimes it can be a desire to shake things up a bit and not to take myself too seriously.