For many Europeans the next decade looks to be filled with threats rather than opportunities.

It is also right that we continue to consult with front line workers and the public to ensure that targets are reasonable and achievable, that measurement regimes are proportionate and that the targets take full account of the other reforms that are under way.

Advances in technology and in our understanding of illness and disease together with an expanded workforce and greater resources will allow us to provide more services to a higher quality.

My view is that targets, properly constructed and applied across public services have been fundamental to past successes and will be an essential part of sustaining progress into the future.

Primary care must never be seen simply as a set of organisational structures.

But effective regulation at the European Union level can make a massive contribution to achieving our shared goals of improving competitiveness, jobs and growth.

As Tony Blair has made clear, our fundamental challenge is how to make Europe work better.

But we can turn challenges into opportunities if we look outwards to the realities of the global economy and modernise our internal institutions in ways that will equip Europe to meet that challenge and create confidence amongst the public.

There is no such thing as free regulation.

And, in the past, it has been all too easy for legislators to load costs onto business in order to meet broader social goals. And costs for business means costs for consumers.

This call for a new culture is not a new idea.

For many Europeans the next decade looks to be filled with threats rather than opportunities.

Having decisions made not in midnight deals but in the light of objective evidence and after consulting those who will be affected should itself provide some reassurance that the EU is trying to reform itself.

Road testing the effects of regulation on European business must become second nature to the European Union.

Greater personal choice, individually tailored services, stronger local accountability, greater efficiency - these are all central to the new direction of travel we have set for our public services.

Some people argue that we should limit choice in favour of good local services. My response is simple: why should we assume those two concepts are mutually exclusive?

Our objective must therefore be to ensure EU better regulation contributes towards delivering a modern European Union which relentlessly focuses on building a dynamic and innovative economy equipped to meet the challenges of the 21st century.

But we need to show that the EU can modernise itself, can adapt to the needs of its citizens, can take their views into account. That will be our ambition for the UK Presidency.

The Civil Service is a vital economic asset to the UK - firstly, in the way it creates a framework for excellence in service delivery and secondly, in how it helps organise the best way to deliver modern public services on which both businesses and individuals depend.

Our aim, during our Presidency in the next six months will be to lead this challenge, to show that Europe can function in a mature and responsible way, to start delivering tangible results that show we are taking people's concerns seriously.

So that we focus not on competing visions for Europe but on what Europe can do to improve economic growth, to give us a cleaner environment, to create more jobs, to make us more secure.

Here in the UK the government has decided to accept the recommendations of the Better Regulation Task Force to measure and make targeted reductions in the administrative costs - the red tape costs - that regulations impose on business.

If we took Chaucer's writings at face value, we'd have to conclude he was a complete drip.

At the heart of these challenges lies the question of how the institutions of the European Union make laws, the types of laws they pass and the effectiveness with which those laws are implemented on civil society and the economy.

More than 50% of significant new regulations that impact on business in the UK now emanate from the EU.

Western Europe GDP per capita - not taking into account the new accession counties - was lower in 2001 relative to that of the US than any time since the 1960's.

But let no one be under any doubt that the scale of the challenge that Europe faces in this emerging global economy is immense and the practical pace of our collective action to meet these challenge to date has just been too slow.

Yet in order to make sure the European social model keeps up with the pace of economic change that is now necessary, the EU must embrace a new approach to lawmaking.

From my time in Health I know that choice empowers people lives.

For too long nurses have been undervalued, restricted in what they could do, with too few career opportunities in clinical practice. For far too long, nurses have endured a pay system that has held them back - both professionally as well as financially.

We must seek to persuade member states and institutions that better regulation in Europe does not mean cutting health and safety in the workplace, nor does it mean dismantling social standards.

The challenge to our national economies and the collective economy of Europe will become - with the growth of China and the continuing productivity growth of the US - even more intense in the decades to come.

For too long nurses have been undervalued, restricted in what they could do, with too few career opportunities in clinical practice. For far too long, nurses have endured a pay system that has held them back “ both professionally as well as financially.

My next house will have not kitchen just vending machines.

I have a lot of self-belief, and I think it will happen. I think I will just get better and better. It's what great players do; they don't let up on anything. And I wouldn't do that anyway.

My father's a deacon, my mother's a choir director, so I grew up in the church and singing in the choir, begging my mom if I could have a solo.

I think humans have always wrestled with the Divine Idea - an idea that unites and separates, creates and destroys, consoles and terrifies. Throughout human history, it is an idea that seems sometimes to have caused whole populations to rise up and slaughter one another.

The thing about science fiction is that it's totally wide open. But it's wide open in a conditional way.

Your home should be about enriching the daily experience.

When we find something new at Giza, we announce it to the world. The Sphinx and the Pyramids are world treasures. We are the guardian's of these treasures, but they belong to the world.

I look for the role that excites me and work with whoever that director happens to be, wherever he wants to shoot the film.

Everything starts and finishes with the soldier.

Teamwork is what makes common people capable of uncommon results.

I prefer to break new ground, but it gets harder and harder with the territory that's already been walked on.

For all the power of video and film, I am not giving up my pen. I am just much more likely to try to link essays to webcasts or videos. The best way for these two media to move forward, to inform and make change, is in tandem; together they are more than the sum of their parts.

I was a product of a divorced family and I used humor as a weapon to combat sadness. I used comedy to make my mother laugh in light of the darkness that she faced, and to me it became a very powerful tool at a very young age, at six. I saw how therapeutic it could be.

Places are part of nature, of the bigger picture. We are interrelated. When we contemplate them in their own right, they can sometimes change our lives; they can become spiritual experiences.

I stay out of politics because if I begin thinking too much about politics, I'll probably... drop writing children's books and become a political cartoonist again.

I saw 'Brokeback Mountain' in a packed house in Chelsea, New York, when I was filming a Bollywood film there. Chelsea, being a predominately gay neighbourhood, had the most euphoric reaction. I saw couples holding hands and crying at the end. It was the most heartening viewing I have ever been to.