MICROFILAMENT D'ACTINE Structure: - globulaire (actine G) - sillon chargé négativement ==> lien avec ATP - plus petit diamètre (5-8nm) — Polymérisation: Les conditions: - KCl - Mg2+ - Actine lié à de l’ATP Les étapes. 1. Nucléation: étape lente, formation d’un trimère d’actine (amorce) 2. Elongation: étape très rapide, ajout des monomères par leur pôle négatif. 3. Équilibre dynamique

David Congiu

BIOLOGIE CELULAIRE

Biologia

biologie

cellule

David Congiu

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Généralités: - Cytosquelette s’étend dans la cellule de la membrane plasmique jusqu'au niveau de la face interne du noyau. - Composé de trois structures protéiques: microfilaments d’actine, filaments intermédiaires et microtubules.

David Congiu

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FILAMENT INTERMÉDIAIRE Structure: - filamenteux ATTENTION, les monomères sont variables selon les cellules.

David Congiu

MICROTUBULES Structure: - globulaire - tubuline alpha et beta. - association avec GTP - plus grand diamètre (25nm)

David Congiu

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