My main efforts focussed on trying to identify the rate controlling steps during the cell cycle. Crucial for this analysis were wee mutants that were advanced prematurely through the cell cycle and so divided at a reduced cell size.

After an extensive interview he arranged for my weaknesses in foreign languages to be over-looked and so I started a Biology degree at Birmingham in 1967.

I was never very good at exams, having a poor memory and finding the examination process rather artificial, and there never seemed to be enough time to follow up things that really interested me.

I am still a keen mountain walker and an enthusiastic glider pilot.

Like many students, I found the drudgery of real experiments and the slowness of progress a complete shock, and at my low points I contemplated other alternative careers including study of the philosophy or sociology of science.

At age 11 in 1960, I moved to an academic state secondary school, Harrow County Grammar School for Boys.

I had a great time investigating the pigments of different mutant fruit flies by following experimental protocols published in Scientific American, and I also remember making my own beetle collection when it was still acceptable to make such collections.

My parents were born in Norfolk and spent their early years working in the big houses of that rural English county, my mother as a cook and my father as a handyman and chauffeur.

My main efforts focussed on trying to identify the rate controlling steps during the cell cycle. Crucial for this analysis were wee mutants that were advanced prematurely through the cell cycle and so divided at a reduced cell size.

My 6 years with Murdoch were pivotal for my entire research career.

This time at Birmingham turned me into a general biologist, and ever since then I have always tried to take a biological approach to any research project that I have undertaken.

I felt strongly that since the pursuit of good science was so difficult it was essential that the problem being studied was an important one to justify the effort expanded.

I think it was this curiosity about the natural world which awoke my early interest in science.

I met my wife Anne who was a sociology student, and her influence together with activities associated with the student movement of the time opened up my interests amongst other things into the theatre, art, music, politics and philosophy.

My parents were neither wealthy nor academic, but we lived comfortably and they were always extremely supportive of my academic efforts and aspirations, both at school and university.

Therefore, I reasoned that study of the cell cycle responsible for the reproduction of cells was important and might even be illuminating about the nature of life.

This possibility bothered me as I thought it was not advisable to remain in one academic environment, and the long dark winters in Edinburgh could be rather dismal.

Better understanding of the natural world not only enhances all of us as human beings, but can also be harnessed for the better good, leading to improved health and quality of life.

During the winter my attention was attracted to the changes in the stars and planets in the sky.

I decided that the University of Sussex in Brighton was a good place for this work because it had a strong tradition in bacterial molecular genetics and an excellent reputation in biology.

I have an idealistic view of science as a liberalising and progressive force for humanity.

It was during my time at secondary school that I abandoned religion.

It has been a privilege to pursue knowledge for its own sake and to see how it might help mankind in more practical ways.

Scientific understanding is often beautiful, a profoundly aesthetic experience which gives pleasure not unlike the reading of a great poem.

A key issue in developmental biology at that time was the problem of how cells underwent differentiation, with most workers concentrating on explanations in terms of changes in enzyme and gene regulation.

I was by far the youngest of the family, and at times it was like being an only child.

Androgyny is not trying to manage the relationship between the opposites; it is simply flowing between them.

We're all like children. We may think we grow up, but to me, being grown up is death, stopping thinking, trying to find out things, going on learning.

I am playing with the assumptions that we have in our everyday life when we are tripped up or fooled and we learn something, that makes things exciting - I am having fun with that stuff, but you have to manage it so it doesn't get too cute, that's what I trying to work toward.

'Thou shalt not get found out' is not one of God's commandments; and no man can be saved by trying to keep it.

Well, I think that those of us in public life that are trying to do a good job, and that are faced with this popular new game that the media has of being critical of everything that anybody in public office does probably are thin-skinned.

When Frank the Pug is singing I Will Survive, the only reason it's funny is that Will is in that shot trying not to get angry. A shot of a dog singing I Will Survive on its own will not get a laugh.

I sometimes lie awake at night trying to think of something funny that Richard Nixon said.

Votes are like trees, if you are trying to build a forest. If you have more trees than you have forests, then at that point the pollsters will probably say you will win.

I'd been trying for all of the eight years we'd been married to have a child, and finally I did.

Yeah; I'm a much better blues player than anybody knows, but being in the kind of group I'm in, we were always trying to make popular records.

Uhm, I'm the one wanting the lessons! I don't want to say too much about it because I'd rather have you see the movie, but he's trying to find his music.

So my idea of neurotic is spending too much time trying to correct a wrong. When I feel that I'm doing that, then I snap out of it.

I've always done food that can work in a set time frame. The message I'm trying to get across is, it doesn't have to take three days to do this. With planning, you can do a lot and really have quality food every day.

I meditate a lot, but I am constantly in pain. I'm trying to live with this. You just have to accept it.

I trained and trained and went up against Kurt, then being a world champion in '94, and after that I did Tommy's tour and then my tour and all this stuff and just trying to deal with it all. And now, I've just kind of backed off a little.

You feel the music needs something but you don't know what. So you start searching, fitting, measuring, trying. Every time you try another angle. And sometimes that's frustrating, especially if you don't come up with something for three days.

Trying to give back a little bit is important.

Intimacy comes from being yourself on the stage and making the audience feel, without trying, that you're sittin' down there with 'em, playing, and that can happen in a big hall, if you have a good audience that want to listen.

While advances in scientific research have led to some new and exciting treatments that have enlarged and enhanced the quality and length of human life, we must not lose sight as to what we are trying to accomplish.

Playing polo is like trying to play golf during an earthquake.

Orlando's a part of me. The next guy's a part of me. And the next guy's a part of me. That's all I'm trying to do, is tell cool stories that people can relate to.

In modelling, there is no point in trying to prove you have a brain, so why even bother? I'd sooner save the energy for something more meaningful.

I have spent more than half a lifetime trying to express the tragic moment.