The greatest grand challenge for any scientist is discovering how to prevent the spread of HIV and finding the cure or an effective vaccine for AIDS.

I wanted to become a mathematician, physicist or astronomer.

I dropped out of high school four times between the ages of 12 to 17.

Nelson Mandela and Malcolm X came out of prison stronger.

I have expertise in five different fields which helps me to easily understand the analogy between my scientific problems and those occurring in nature.

I preferred to study those subjects that were of interest to me.

Adversities such as being homeless and going to prison has made many people stronger.

Due to financial reasons, I dropped out of school after eight years of formal schooling.

When I enrolled in college at age 19, I had a total of eight years of formal classroom education. As a result, I was not comfortable with formal lectures and receiving regular homework assignments.

Our lives sometimes depend on computers performing as predicted.

The 65,536 processors were inside the Connection Machine.

One out of every 100 American men is HIV positive. The rate of infection has reached epidemic proportions in 40 developing nations.

During the week that I arrived in the United States, I saw an airport, used a telephone, used a library, talked with a scientist, and was shown a computer for the first time in my life.

Briefly, to program it requires an absolute understanding of how all 65,536 processors are interconnected.

The Connection Machine was the most powerful supercomputer in the world. It is a complex supercomputer and it will take forever to completely describe how it works.

Because I believe that humans are computers, I conjectured that computers, like people, can have left- and right-handed versions.

Eighty percent of Americans with HIV do not know they are infected.

First, I identify an analogous problem in nature and borrow from it.

The Connection Machines owned by the United States government laboratories were made available to me because they were considered impossible to program and there was no great demand for them at that time.

The hardships that I encountered in the past will help me succeed in the future.

The labs were happy that I was brave enough to attempt to program it and the $5 million computer was left entirely to my use. I was their human guinea pig.

My focus is not on solving nature's deeper mysteries. It is on using nature's deeper mysteries to solve important societal problems.

It is smarter to borrow from nature than to reinvent the wheels.

Because I am not formally trained in the medical sciences, I can bring in new ideas to AIDS research and the cross-fertilization of ideas from different fields could be a valuable contribution to finding the cure for AIDS.

The hardship of living in a refugee camp made me psychologically strong.

Nigeria is a West African nation of over 100 million energetic people. It is endowed with lots of natural resources but lacks human resources.

The greatest grand challenge for any scientist is discovering how to prevent the spread of HIV and finding the cure or an effective vaccine for AIDS.

Roosevelt's magic lay in one facet of his personality: He knew how to take the risk. No other man in public life I knew could so readily take the challenge of the new.

To do the Ozzfest again would be great. I'd like to finish with a final Sabbath album. You always feel that it is still a challenge.

People are not perfect... very often the relationships that are strongest are those where people have worked through big crises, but they've had to work through them. So the challenge to us is to work through that.

Every single book is a challenge.

Critics are sentinels in the grand army of letters, stationed at the corners of newspapers and reviews, to challenge every new author.

The lopsided attitudes of college professors pose a serious challenge to learning because students are so susceptible to becoming lopsided sheep.

I really enjoy comedy. It's a real challenge.

I had a hard time with that hockey. I hadn't grown up skating, so that was my biggest challenge. We worked on it and worked on it. But then when we first shot it, it was so hard for me.

The challenge is to practice politics as the art of making what appears to be impossible, possible.

Change can either challenge or threaten us. Your beliefs pave your way to success or block you.

My greatest challenge has been to change the mindset of people. Mindsets play strange tricks on us. We see things the way our minds have instructed our eyes to see.

I'd say that it's important for music to be there that gives you a challenge, that rearranges things in your head.

I like good stories. Quality products and character are what's important. Even if the script isn't that strong, if I challenge myself with a great character, I'll go for it.

I tend to arrive in the rehearsal process with very strongly developed ideas about what I want to do. But I don't like those ideas to be things that are not subject to change, or subject to development, or subject to challenge.

I'm not looking to set a standard... but, I believe I have offered a challenge to others with my work.

If you live a life of make-believe, your life isn't worth anything until you do something that does challenge your reality. And to me, sailing the open ocean is a real challenge, because it's life or death.

And, I'd never done Tennessee Williams, and I had done Broadway musicals, so it was a challenge.

When you remove the risk, you remove the challenge. When you remove the challenge, you wither on the vine.

After Land I wanted to continue exploring the theme but I needed a new challenge so turned to colour. I explored Bradford and produced a series of urban landscapes that I liked, but because Land had made such an impact on the general public my colour work wasn't reviewed.

The worlds I paint leave a lot to engage the imagination by hinting at what lies beyond the four edges of the painting. I think getting beyond the four edges of an opportunity or challenge is one of the basic skills you need in business.

For me, it's a bigger challenge, it's much harder to do and much more rewarding to do well, then just to think up stuff of your own, hit or miss, because you've got to see to it that you don't torpedo any of his punch lines.

This same habitual blindness to spiritual, substantive dimensions of every significant challenge continues to handicap Hollywood.