In modern pharmacology it's so clear that even if you have a fixed dose of a drug, the individuals respond very differently to one and the same dose.

Well, in pharmacology, if the effect is local, it's of course absolutely awkward to use it in any other way than as a local treatment.

In modern pharmacology it's so clear that even if you have a fixed dose of a drug, the individuals respond very differently to one and the same dose.

Fluorine has a protecting action against caries, but this is a local effect. If you drink it, you are running the risk of all kinds of toxic actions.

I think marrying somebody who's not a celebrity, it just takes a lot of the pressure off.

Metaphysical speculation is independent of the physical validity of the Big Bang itself and is irrelevant to our understanding of it.

In the political confusion and the torrid heat, I convinced myself that Madrid was the world's stomach and that I had been chosen for the task of restoring this digestive organ to health.

I am not a fancy cook or an ambitious cook. I am a plain old cook.

You can't master your future if you're still a slave to your past.

You have to do it yourself, no one else will do it for you. You must work out your own salvation.

In contemporary art culture, where good looks and clever strategic planning of art careers have become a feature, professional practice may be taught in art schools like a branch of public relations or political science.

Human life is everywhere a state in which much is to be endured and little to be enjoyed.

California club pop chirper Dev's debut is as stark as it is sweet. This is owed partly to the casually giddy lightness of her talk-singing - familiar from her slizzered 2010 cameo on Far East Movement's smash 'Like a G6,' and around-the way-girl frisky like 1980s Latin freestyle.

A large majority of Americans believe that the U.N., not the U.S., should take the lead in working with Iraqis to transfer authentic sovereignty as well as in economic reconstruction and maintaining civic order.

I speak my mind. I'm not really afraid of things. I actually don't think that's that unusual.

The only realistic choice is to follow your dreams.

I grew up in Birmingham, where they made useful things and made them well.

It’s really important to stand up for yourself and not always agree with what people say if indeed you don’t feel that that’s true.

You convey something that the public either trusts or it does not trust, and it has to do with the content and how you handle the news, but it also just has something to do with your persona.

As you have learnt something of time, value and make a proper use of it. Once past, it knows no return; how necessary, then, that you spend it in improving your mind and fitting it for future happiness and usefulness.

As a parent, I'd - I'd be a better father.

I wish they would only take me as I am.

Don't stink up the place with bad acting, if an opportunity comes your way.

Our problem right now is that we're so specialized that if the lights go out, there are a huge number of people who are not going to know what to do. But within every dystopia there's a little utopia.

If my history, my indisputable British history, has never been visited, where does that put me? If we are only going to look at things that need a revisit, you are wiping me out of this country's history. That is unacceptable to me.

I've been into horror movies ever since I was five years old.

You need people around you that care about you and are thinking about you in your best interest. And keep your mind straight.

Just don't give up trying to do what you really want to do. Where there is love and inspiration, I don't think you can go wrong.