That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin.

As has repeatedly been stated, the underlying hypothesis, which in a number of cases has been supported by direct experimental evidence, is that each gene controls the production, function, and specificity of a particular enzyme.

In microbiology the roles of mutation and selection in evolution are coming to be better understood through the use of bacterial cultures of mutant strains.

That the primary effect of gene mutation may be as simple as the substitution of a single amino acid by another and may lead to profound secondary changes in protein structure and properties has recently been strongly indicated by the work of Ingram on hemoglobin.

The present contains nothing more than the past, and what is found in the effect was already in the cause.

Bambi has a profound effect on children because it's about losing your mother.

To believe in a just law of cause and effect, carrying with it a punishment or a reward, is to believe in righteousness.

Our estimates suggest that a tax increase of 1 percent of GDP reduces output over the next three years by nearly 3 percent. The effect is highly significant.

The truth is, it's not a great career move to create a readership and then, in effect, abandon them.

I am for an art that takes into account the direct effect of the elements as they exist from day to day apart from representation.

Planets are too dim to be detected with existing equipment, far away, except in these very special circumstances where they're seen by their gravitational effect.

Well, in pharmacology, if the effect is local, it's of course absolutely awkward to use it in any other way than as a local treatment.

Writing songs has a therapeutic effect, and it either kills off love or wins the heart of the lover.

The good news was that Enterprise and the newly arrived Yorktown had attacked the Marshall and Gilbert islands. Those attacks had a great effect on morale.

Motherhood has a very humanizing effect. Everything gets reduced to essentials.

The Tax Code today is more complicated than ever, and the very people on the Republican side who denounce the Tax Code's complexity are the ones that put together what they now call a convoluted monstrosity. They put it into effect.

If the many allegations made to this date are true, then the burglars who broke into the headquarters of the Democratic National Committee at the Watergate were, in effect, breaking into the home of every citizen.

It would be great to take one city street and turn it into a pedestrian corridor and see what kind of effect it has on the businesses in that area - It's the future I think.

To enlarge or illustrate this power and effect of love is to set a candle in the sun.

The cause is hidden; the effect is visible to all.

Logic, like whiskey, loses its beneficial effect when taken in too large quantities.

The Vietnamese have a secret weapon. It's their willingness to die beyond our willingness to kill. In effect, they've been saying, You can kill us, but you'll have to kill a lot of us; you may have to kill all of us. And, thank heaven, we are not yet ready to do that.

The oppression of any people for opinion's sake has rarely had any other effect than to fix those opinions deeper, and render them more important.

In America you can say anything you want - as long as it doesn't have any effect.

Scientific men can hardly escape the charge of ignorance with regard to the precise effect of the impact of modern science upon the mode of living of the people and upon their civilisation.

It becomes a giant's task to compute the result when the effect of cross seas, wind at all angles and ever varying force, arched surfaces, head resistance, ratio of weight to area, and the intelligence of the guiding power crop up.

I am above the weakness of seeking to establish a sequence of cause and effect, between the disaster and the atrocity.

The question at the end of the day was, the courts having found there was no defense, a producer about to go to jail, should CBS in effect tell the producer go to jail even though there is no law at all that we can use to get you out of jail?

All we need is a meteorologist who has once been soaked to the skin without ill effect. No one can write knowingly of the weather who walks bent over on wet days.

Few speeches which have produced an electrical effect on an audience can bear the colourless photography of a printed record.

If you do things with a certain type of result and cause a certain type of reaction or effect, then you increase your market value. It's very much a competition for the entertainment dollar, and that's never been more clearly evident than in today's NBA game.

The automobile, both a cause and an effect of this decentralization, is ideally suited for our vast landscape and our generally confused and contrary commuting patterns.

As the cost of gasoline rises and our dependence on foreign oil continues to increase, the effect of sending over $100 billion each year to OPEC nations hurts every American.

This submission is a restraint of liberty, but could be of no effect as to the good intended, unless it were general; nor general, unless it were natural.

Nothing exists from whose nature some effect does not follow.

It can have its effect only through the intervention of God, inasmuch as in the ideas of God a monad rightly demands that God, in regulating the rest from the beginning of things, should have regard to itself.

I'm not a good enough singer to pull off the effect.

What postmodernism gives us instead is a multicultural defense for male violence - a defense for it wherever it is, which in effect is a pretty universal defense.

I conceived of an instrument that would create sound without using any mechanical energy, like the conductor of an orchestra. The orchestra plays mechanically, using mechanical energy; the conductor just moves his hands, and his movements have an effect on the music artistry.

One blob of red in the wrong place and the audience isn't looking at the hero, they're looking at a patch of curtain (or something similar) and your whole effect is lost.

Excess on occasion is exhilarating. It prevents moderation from acquiring the deadening effect of a habit.

The Chancellor also in effect asks us to bargain away whatever obligation or interest we have as regards the neutrality of Belgium. We could not entertain that bargain either.

What is the effect of unlimited coinage of silver in this country? and I invite your attention to this particularly, because it is a question of vital importance.

I'm officially middle-aged. I don't need drugs anymore, thank God. I can get the same effect just by standing up real fast.

Rock musicians, and a vast array of popular-music musicians, due to their wealth, acquired through the mass of their notoriety, are able to be listened to and heard and thus are able to effect change on an international level.

I love that feeling of being in love, the effect of having butterflies when you wake up in the morning. That is special.

The conscious purpose of science is control of Nature; its unconscious effect is disruption and chaos.

But any big change is more likely to result if there is a disruptive event such as new technologies or platforms that have a surprising effect on market share.

A thousand acres that can feed a thousand souls is better than ten thousand acres of no more effect.