Acting with creatures that aren't there is kind like acting with an actor who refuses to come out of his trailer. You still have to go on and do the scene.
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For every successful actor or actress, there are countless numbers who don't make it. The name of the game is rejection. You go to an audition and you're told you're too tall or you're too Irish or your nose is not quite right. You're rejected for your education, you're rejected for this or that and it's really tough.