People ask me if I ever feel outside the Hollywood loop, and I never do, because both of us do a lot of theatre, so it's great for New York and it's also half-way between Europe and the west coast, so it's the best of both worlds.
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For every successful actor or actress, there are countless numbers who don't make it. The name of the game is rejection. You go to an audition and you're told you're too tall or you're too Irish or your nose is not quite right. You're rejected for your education, you're rejected for this or that and it's really tough.