In Darwin's time all of biology was a black box: not only the cell, or the eye, or digestion, or immunity, but every biological structure and function because, ultimately, no one could explain how biological processes occurred.

In order to say that some function is understood, every relevant step in the process must be elucidated.

Biology has progressed tremendously due to the model that Darwin put forth. But the black boxes Darwin accepted are now being opened, and our view of the world is again being shaken.

Skin is made in large measure of a protein called collagen.

This fact immediately suggested a singular event - that at some time in the distant past the universe began expanding from an extremely small size. To many people this inference was loaded with overtones of a supernatural event - the creation, the beginning of the universe.

The point here is that physics followed the data where it seemed to lead, even though some thought the model gave aid and comfort to religion.

In many biological structures proteins are simply components of larger molecular machines.

A man from a primitive culture who sees an automobile might guess that it was powered by the wind or by an antelope hidden under the car, but when he opens up the hood and sees the engine he immediately realizes that it was designed.

The basic structure of proteins is quite simple: they are formed by hooking together in a chain discrete subunits called amino acids.

It is often said that science must avoid any conclusions which smack of the supernatural.

But sequence comparisons simply can't account for the development of complex biochemical systems any more than Darwin's comparison of simple and complex eyes told him how vision worked.

In Darwin's time all of biology was a black box: not only the cell, or the eye, or digestion, or immunity, but every biological structure and function because, ultimately, no one could explain how biological processes occurred.

The question of how the eye works - that is, what happens when a photon of light first impinges on the retina - simply could not be answered at that time.

The theory of undirected evolution is already dead, but the work of science continues.

Science is not a game in which arbitrary rules are used to decide what explanations are to be permitted.

It was only about sixty years ago that the expansion of the universe was first observed.

We are not inferring design to account for a black box, but to account for an open box.

Thus it seemed to Haeckel that such simple life could easily be produced from inanimate material.

By irreducibly complex I mean a single system composed of several well-matched, interacting parts that contribute to the basic function, wherein the removal of any one of the parts causes the system to effectively cease functioning.

Although Darwin was able to persuade much of the world that a modern eye could be produced gradually from a much simpler structure, he did not even attempt to explain how the simple light sensitive spot that was his starting point actually worked.

Throughout history there have been many other examples, similar to that of Haeckel, Huxley and the cell, where a key piece of a particular scientific puzzle was beyond the understanding of the age.

It was a shock to people of the nineteenth century when they discovered, from observations science had made, that many features of the biological world could be ascribed to the elegant principle of natural selection.

Since natural selection requires a function to select, an irreducibly complex biological system, if there is such a thing, would have to arise as an integrated unit for natural selection to have anything to act on.

Proteins are the machinery of living tissue that builds the structures and carries out the chemical reactions necessary for life.

It is a shock to us in the twentieth century to discover, from observations science has made, that the fundamental mechanisms of life cannot be ascribed to natural selection, and therefore were designed. But we must deal with our shock as best we can and go on.

In the 19th century the anatomy of the eye was known in great detail and the sophisticated mechanisms it employs to deliver an accurate picture of the outside world astounded everyone who was familiar with them.

As can be seen even by this limited number of examples proteins carry out amazingly diverse functions.

The conclusion of design flows naturally from the data we should not shrink from it we should embrace it and build on it.

With an eye made quiet by the power of harmony, and the deep power of joy, we see into the life of things.

Happiness is the harvest of a quiet eye.

It is reasonable to have perfection in our eye that we may always advance toward it, though we know it can never be reached.

To judge between good or bad, between successful and unsuccessful would take the eye of a God.

The plate at each point only sends back to the eye the simple colour imprinted. The other colours are destroyed by interference. The eye thus perceives at each point the constituent colour of the image.

One gets into a strange psychological, almost hypnotic, state of mind while on the firing line which probably prevents the mind's eye from observing and noticing things in a normal way.

Don't forget that the only two things people read in a story are the first and last sentences. Give them blood in the eye on the first one.

More firm and sure the hand of courage strikes, when it obeys the watchful eye of caution.

A cynic is a man who looks at the world with a monocle in his mind's eye.

The eye with which I see God is the same eye with which God sees me.

If your sister is in a tearing hurry to go out and cannot catch your eye, she's wearing your best sweater.

Baseball is a game where a curve is an optical illusion, a screwball can be a pitch or a person, stealing is legal and you can spit anywhere you like except in the umpire's eye or on the ball.

Only a kind person is able to judge another justly and to make allowances for his weaknesses. A kind eye, while recognizing defects, sees beyond them.

I tell you the truth, it is hard for a rich man to enter the kingdom of heaven. Again I tell you, it is easier for a camel to go through the eye of a needle than for a rich man to enter the kingdom of heaven.

Nothing contributes so much to tranquilize the mind as a steady purpose - a point on which the soul may fix its intellectual eye.

I don't see any kind of mirror of power, male power, that is, as a form of liberation. I don't believe in an eye for an eye. I don't believe this is truly freedom.

Follow the wisdom of the great actor, James Cagney, you hit your mark, you look the other guy in the eye, and you tell the truth.

Thou has a thousand eyes and yet not one eye; Thou host a thousand forms and yet not one form.

Our situation here, without any exaggeration, is beyond description almost; it is such as eye has not seen nor ear heard, nor hath it ever entered into the heart of men to conceive Boston ever to arrive at.

Every day you must arise and say to your heart, I have suffered enough and now I must live because the light of the sun must not be wasted, it must not be lost without an eye to appreciate it.

Every age has a keyhole to which its eye is pasted.