In the 19th century the anatomy of the eye was known in great detail and the sophisticated mechanisms it employs to deliver an accurate picture of the outside world astounded everyone who was familiar with them.

In order to say that some function is understood, every relevant step in the process must be elucidated.

Biology has progressed tremendously due to the model that Darwin put forth. But the black boxes Darwin accepted are now being opened, and our view of the world is again being shaken.

Skin is made in large measure of a protein called collagen.

This fact immediately suggested a singular event - that at some time in the distant past the universe began expanding from an extremely small size. To many people this inference was loaded with overtones of a supernatural event - the creation, the beginning of the universe.

The point here is that physics followed the data where it seemed to lead, even though some thought the model gave aid and comfort to religion.

In many biological structures proteins are simply components of larger molecular machines.

A man from a primitive culture who sees an automobile might guess that it was powered by the wind or by an antelope hidden under the car, but when he opens up the hood and sees the engine he immediately realizes that it was designed.

The basic structure of proteins is quite simple: they are formed by hooking together in a chain discrete subunits called amino acids.

It is often said that science must avoid any conclusions which smack of the supernatural.

But sequence comparisons simply can't account for the development of complex biochemical systems any more than Darwin's comparison of simple and complex eyes told him how vision worked.

In Darwin's time all of biology was a black box: not only the cell, or the eye, or digestion, or immunity, but every biological structure and function because, ultimately, no one could explain how biological processes occurred.

The question of how the eye works - that is, what happens when a photon of light first impinges on the retina - simply could not be answered at that time.

The theory of undirected evolution is already dead, but the work of science continues.

Science is not a game in which arbitrary rules are used to decide what explanations are to be permitted.

It was only about sixty years ago that the expansion of the universe was first observed.

We are not inferring design to account for a black box, but to account for an open box.

Thus it seemed to Haeckel that such simple life could easily be produced from inanimate material.

By irreducibly complex I mean a single system composed of several well-matched, interacting parts that contribute to the basic function, wherein the removal of any one of the parts causes the system to effectively cease functioning.

Although Darwin was able to persuade much of the world that a modern eye could be produced gradually from a much simpler structure, he did not even attempt to explain how the simple light sensitive spot that was his starting point actually worked.

Throughout history there have been many other examples, similar to that of Haeckel, Huxley and the cell, where a key piece of a particular scientific puzzle was beyond the understanding of the age.

It was a shock to people of the nineteenth century when they discovered, from observations science had made, that many features of the biological world could be ascribed to the elegant principle of natural selection.

Since natural selection requires a function to select, an irreducibly complex biological system, if there is such a thing, would have to arise as an integrated unit for natural selection to have anything to act on.

Proteins are the machinery of living tissue that builds the structures and carries out the chemical reactions necessary for life.

It is a shock to us in the twentieth century to discover, from observations science has made, that the fundamental mechanisms of life cannot be ascribed to natural selection, and therefore were designed. But we must deal with our shock as best we can and go on.

In the 19th century the anatomy of the eye was known in great detail and the sophisticated mechanisms it employs to deliver an accurate picture of the outside world astounded everyone who was familiar with them.

As can be seen even by this limited number of examples proteins carry out amazingly diverse functions.

The conclusion of design flows naturally from the data we should not shrink from it we should embrace it and build on it.

Consistency is found in that work whose whole and detail are suitable to the occasion. It arises from circumstance, custom, and nature.

I never regret anything. Because every little detail of your life is what made you into who you are in the end.

The difference between something good and something great is attention to detail.

I suppose that I was a kind of consultant for taste. Is it good taste? Or bad taste? I had an attention to detail, to what would tell best the story. Because many people get excited about the work and drift off from the story.

A lot of our entertainment throws into detail the stagnation and illness of how we live today-it's sad and it's sick... and it's profitable.

There are a lot of times that if a detail in a scene or a beat, feels unnatural, they'll allow me to explore another direction to go until we're all comfortable with what we are doing.

The day Tarzan opened in London, I sat in a hotel room and discussed the project in detail.

If you take a book of a thousand pages on the Second World War, in which 50 million people died, the concentration camps occupy two pages and the gas chambers ten or 15 lines, and that's what one calls a detail.

In writing a series of stories about the same characters, plan the whole series in advance in some detail, to avoid contradictions and inconsistencies.

We are going to have a huge Oscar issue, you are going to see everything in such beautiful detail.

I won't go into detail but this animated one, the story line is very cool and the kids seem to love it.

My writing style is very sensual, as in sensory detail.

To create something exceptional, your mindset must be relentlessly focused on the smallest detail.

The level of detail and craft is something that's inscribed within the original design concept. And so when I begin to draw, I know what kind of detailing I want the building to have.

The art of motherhood involves much silent, unobtrusive self-denial, an hourly devotion which finds no detail too minute.

Disney is thrilling and informative and important and beautiful and suspect. Butts was a detail I observed later and definitely ties in. I suppose I was programmed, yeah.

Our life is frittered away by detail... simplify, simplify.

I'm blown away by the graphical detail of today's games. I can't imagine that it's going to get any better, but it's just going to continually progress and soon we'll be living in that world.

In the successful organization, no detail is too small to escape close attention.

The really big difference is that what you make with a molecular machine can be completely precise, down to the tiniest degree of detail that can exist in the world.

Culture is a way of coping with the world by defining it in detail.