The long, cold Minnesota winters instilled in me a fascination for exotic far off places; I aspired toward a career in tropical diseases and world health problems.

It is a remarkable honor to receive a Nobel Prize, because it not only recognizes discoveries, but also their usefulness to the advancement of fundamental science.

The Department of Cell Biology at Johns Hopkins was founded and directed by Tom Pollard, an engaging young scientist with remarkable energy and enthusiasm.

My brother Jim and I spent many wonderful summers working on dairy farms in Wisconsin owned by Mom's cousins, and as members of our local Boy Scout troop.

My goal was to develop into an independent research scientist studying clinical problems at the laboratory bench, but I felt that postgraduate residency training in internal medicine was necessary.

We always had lutefisk for Christmas dinner, after which Dad read from the Norwegian Bible.

In 1862, Abraham Lincoln signed the Homestead Act, a bill opening one half million square miles of territory in the western United States for settlement.

Following my junior year in high school, I went on a camping trip through Russia in a group led by Horst Momber, a young language teacher from Roosevelt.

Our lab had always refrained from keeping our studies secret.

The long, cold Minnesota winters instilled in me a fascination for exotic far off places; I aspired toward a career in tropical diseases and world health problems.

Johns Hopkins introduced me to two defining events in my life: commitment to biomedical research and meeting my future wife, Mary.

Dad was a chemistry professor at Saint Olaf College in Minnesota, then Oxford College in Minnesota, and a very active member of the American Chemical Society education committee, where he sat on the committee with Linus Pauling, who had authored a very phenomenally important textbook of chemistry.

Every cell in our body is primarily water. But the water doesn't just sit in the cell, it moves through it in a very organized way. The process occurs rapidly in tissues that have these aquaporins or water channels.

I grew up in Minnesota. Four generations of my father's people are buried there.

In science, one should use all available resources to solve difficult problems. One of our most powerful resources is the insight of our colleagues.

Mother had to support herself at age 18 because it was during the depression and when my grandfather lost the farm and there was no place for her; she worked as an assistant to a maid.

Natural selection is not an inflammatory phrase; evolution is.

Now a cholera epidemic was sweeping through Southeast Asia and south Asia in the early 1970s, so I started medical school and I joined a laboratory to work on this.

Now in the 21st century, the boundaries separating chemistry, physics, and medicine have become blurred, and as happened during the Renaissance, scientists are following their curiosities even when they run beyond the formal limits of their training.

Often times the public school teachers are ridiculed or they are made to feel inferior but this is really undeserved.

So, my advice to young scientists is, think critically about your work; probably don't blab unnecessarily.

Until 1985, when my lab found the protein they are made of, aquaporins hadn't yet been identified. There had been a controversy in biology for more than 100 years about how water moved through cells.

Water is commonly regarded as the 'solvent of life,' since our bodies are 70% water. All other vertebrates, invertebrates, microbes, and plants are also primarily water. The organization of water within biological compartments is fundamental to life, and the aquaporins serve as the plumbing systems for cells.

Well, all life forms are dependent upon water.

Well, my take was people of Minnesota, these are good people. They're in many ways more generous than other parts of the country. They're better educated than other parts of the country.

While the lab plays an enormous role, research is also influenced by inner peace of mind and one's family environment, depending on what stage of one's life and career a scientist is at.

Written in 1895, Alfred Nobel's will endowed prizes for scientific research in chemistry, physics, and medicine. At that time, these fields were narrowly defined, and researchers were often classically trained in only one discipline. In the late 19th century, knowledge of science was not a requisite for success in other walks of life.

My mother keeps things in perspective for me. She makes me realize that the acting I do and love is no more important than what one of my brothers does-he works in a shoe repair shop. If my career ever tapers off, I'll go to college.

An unexpected benefit of my career in biochemistry has been travel.

I'm sure once my career's over, when I look back when I'm older, I can maybe appreciate it a little bit more.

In Hungary, acting is a career for which one fits himself as earnestly as one studies for a degree in medicine, law, or philosophy.

I have been driven demented in my career.

The blues is something separate from what I do. They connect at certain spots, but blues is different. I wouldn't put it in with what my career has been. That would be a whole separate wing.

I wanted to be an actress. In college I was a serious feminist and very political. I was determined to get one thing out of my career and that was respect. I didn't want money. I didn't care about fame.

It could be my downfall, but I don't think it is - Hollywood is run on perception, and if you stray off the path of what you want to do with your career, it's suicide.

Those who joined us for selfish personal reasons, for a career or other motives will be the ones to leave.

Warren Beatty took an interest in my career at one point.

I knew an actor's career goes up and down and back up again. Your standing in this business can't be your whole identity; otherwise, you're doomed.

The biggest break in my career was getting into the Beatles in 1962. The second biggest break since then is getting out of them.

Sometimes you get caught up in what's going on around you. The reality is that you are just a regular person. At some point, the career will be over, the bright lights turn off. That can come back to haunt you if you're not just a regular guy.

The truth is, it's not a great career move to create a readership and then, in effect, abandon them.

I grew up wanting to make movies, and along the way I suddenly found that I had a career doing comedy.

Music is the career I'm lucky enough to get paid for, but I have other desires and passions.

I think to just single out a highlight of Elvis's career is pretty much impossible. As far as being a fan of his, a lifetime fan, there were just too many highlights.

Clearly, society has a tremendous stake in insisting on a woman's natural fitness for the career of mother: the alternatives are all too expensive.

I have probably purchased fifty 'hot tips' in my career, maybe even more. When I put them all together, I know I am a net loser.

I've spent my career trying to help people without connections understand what's going on so that they have a chance of getting a fair shake from the connected and the powerful.

If I had my career to play over, one thing I'd do differently is swing more. Those 1,200 walks I got, nobody remembers them.

Superstar was made so early in my career I had nothing to do with it at all. The first time I saw it was the opening screening.