To those of you who study history, economics, sociology, literature and language I present the challenge of the utilization of the enormous resources in our grasp to the problem of creating a genuinely good life for yourselves and your children.

I feel, sometimes, as the renaissance man must have felt in finding new riches at every point and in the certainty that unexplored areas of knowledge and experience await at every turn.

The destiny of our society is yours to make and you have a vastly greater importance to the world than we do.

The increase of scientific knowledge lies not only in the occasional milestones of science, but in the efforts of the very large body of men who with love and devotion observe and study nature.

I count myself fortunate to be able to participate in the life of science in this era.

If, on occasion, the knowledge brought by science leads to an unhappy end, this is not to the discredit of science but is rather an indication of an imperfect ability to use wisely the gifts placed within our hands.

No single achievement in science is possible without the painstaking work of the many hundreds who have built the foundation on which all new work is based.

Indeed science alone may perhaps be sterile when pursued without an understanding of the world in which scientific knowledge is created and in which the fruits of science are used.

Science shows us truth and beauty and fills each day with a fresh wonder of the exquisite order which governs our world.

To those of you who study history, economics, sociology, literature and language I present the challenge of the utilization of the enormous resources in our grasp to the problem of creating a genuinely good life for yourselves and your children.

Science is the greatest creative impulse of our time. It dominates the intellectual scene and forms our lives, not only in the material things which it has given us, but also in that it guides our spirit.

The knowledge and understanding of the world which science gives us and the magnificent opportunity which it extends to us to control and use the world for the extension of our pleasure in it has never been greater than it now is.

We live, I think, in the century of science and, perhaps, even in the century of physics.

Roosevelt's magic lay in one facet of his personality: He knew how to take the risk. No other man in public life I knew could so readily take the challenge of the new.

To do the Ozzfest again would be great. I'd like to finish with a final Sabbath album. You always feel that it is still a challenge.

People are not perfect... very often the relationships that are strongest are those where people have worked through big crises, but they've had to work through them. So the challenge to us is to work through that.

Every single book is a challenge.

Critics are sentinels in the grand army of letters, stationed at the corners of newspapers and reviews, to challenge every new author.

The lopsided attitudes of college professors pose a serious challenge to learning because students are so susceptible to becoming lopsided sheep.

I really enjoy comedy. It's a real challenge.

I had a hard time with that hockey. I hadn't grown up skating, so that was my biggest challenge. We worked on it and worked on it. But then when we first shot it, it was so hard for me.

The challenge is to practice politics as the art of making what appears to be impossible, possible.

Change can either challenge or threaten us. Your beliefs pave your way to success or block you.

My greatest challenge has been to change the mindset of people. Mindsets play strange tricks on us. We see things the way our minds have instructed our eyes to see.

I'd say that it's important for music to be there that gives you a challenge, that rearranges things in your head.

I like good stories. Quality products and character are what's important. Even if the script isn't that strong, if I challenge myself with a great character, I'll go for it.

I tend to arrive in the rehearsal process with very strongly developed ideas about what I want to do. But I don't like those ideas to be things that are not subject to change, or subject to development, or subject to challenge.

I'm not looking to set a standard... but, I believe I have offered a challenge to others with my work.

If you live a life of make-believe, your life isn't worth anything until you do something that does challenge your reality. And to me, sailing the open ocean is a real challenge, because it's life or death.

And, I'd never done Tennessee Williams, and I had done Broadway musicals, so it was a challenge.

When you remove the risk, you remove the challenge. When you remove the challenge, you wither on the vine.

After Land I wanted to continue exploring the theme but I needed a new challenge so turned to colour. I explored Bradford and produced a series of urban landscapes that I liked, but because Land had made such an impact on the general public my colour work wasn't reviewed.

The worlds I paint leave a lot to engage the imagination by hinting at what lies beyond the four edges of the painting. I think getting beyond the four edges of an opportunity or challenge is one of the basic skills you need in business.

For me, it's a bigger challenge, it's much harder to do and much more rewarding to do well, then just to think up stuff of your own, hit or miss, because you've got to see to it that you don't torpedo any of his punch lines.

This same habitual blindness to spiritual, substantive dimensions of every significant challenge continues to handicap Hollywood.

Every artist has to grow, and has to challenge themselves with a new form of expression.

The next challenge for Christianity is to remind Europeans that we are called to seek the truth.

Give yourself an even greater challenge than the one you are trying to master and you will develop the powers necessary to overcome the original difficulty.

The biggest challenge has been simulating a tornado with wind machines and dirt and debris. Right when you walk on the set, you feel the energy of a tornado. But the hardest thing is trying to get dialogue out in all of that.

I look at raising funds for The Perlman Music Program as a challenge and as a way to provide opportunities for people who care about the future of classical music.

My father instilled in me the attitude of prevailing. If there's a challenge, go for it. If there's a wall to break down, break it down.

The challenge in working in politics, particularly if you're working for a political party, is that everyone's a messenger.

People should not be imprisoned without having the ability to challenge the legality of that imprisonment.

Every Teen Challenge ministry is responsible for raising its own finances, but we assist these works with finances, prayer and counseling, especially overseas in areas such as Siberia, Africa, South America.

It took me about 12 years to reach my million-word mark. The challenge now is to continue to challenge myself.

Roddick can challenge him as well if he serves big consistently for the entire match. If he does that, then he is tough to break even for a guy like Federer.

It was depressing, very depressing. I worried about how I would make a living. I didn't want to stay on the farm. It didn't offer the challenge I wanted and yet, without a college education, I felt that I was really out of luck.

The challenge we have in the war on terrorism is looking around for those pieces that matter and trying to fit them together.

My dad always used to tell me that if they challenge you to an after-school fight, tell them you won't wait-you can kick their ass right now.