The major novelty of my theory was its claim that the most rapid evolutionary change does not occur in widespread, populous species, as claimed by Most geneticists, but in small founder populations.

All I claimed was that when a drastic change occurs, it occurs in a relatively small and isolated population.

Most of them are doomed to rapid extinction, but a few may make evolutionary inventions, such as physiological, ecological, or behavioral innovations that give these species improved competitive potential.

Life is simply the reification of the process of living.

Evolution thus is merely contingent on certain processes articulated by Darwin: variation and selection.

The major novelty of my theory was its claim that the most rapid evolutionary change does not occur in widespread, populous species, as claimed by Most geneticists, but in small founder populations.

It seems to me that for Darwin the pulsing of evolutionary rates was a strictly vertical phenomenon.

I did not claim that speciation occurs only in founder populations.

According to the concept of transformational evolution, first clearly articulated by Lamarck, evolution consists of the gradual transformation of organisms from one condition of existence to another.

As a consequence, geneticists described evolution simply as a change in gene frequencies in populations, totally ignoring the fact that evolution consists of the two simultaneous but quite separate phenomena of adaptation and diversification.

Living in an entirely different physical as well as biotic environment, such a population would have unique opportunities to enter new niches and to select novel adaptive pathways.

New gene pools are generated in every generation, and evolution takes place because the successful individuals produced by these gene pools give rise to the next generation.

I had found again and again that the most aberrant population of a species - often having reached species rank, and occasionally classified even as a separate genus - occurred at a peripheral location, indeed usually at the most isolated peripheral location.

Indeed, I was unable to find any evidence whatsoever of the occurrence of a drastic evolutionary acceleration and genetic reconstruction in widespread, populous species.

In those early years in New York when I was a stranger in a big city, it was the companionship and later friendship which I was offered in the Linnean Society that was the most important thing in my life.

In neither his definition nor the examples illustrating what memes are does Dawkins mention anything that would distinguish memes from concepts.

Scientific progress consists in the development of new concepts.

We used to think that revolutions are the cause of change. Actually it is the other way around: change prepares the ground for revolution.

I must stress here the point that I appreciate clarity, order, meaning, structure, rationality: they are necessary to whatever provisional stability we have, and they can be the agents of gradual and successful change.

Excuses change nothing, but make everyone feel better.

So, first you have to be able to play with a metronome. Then you take your freedom. If you play in an orchestra, you got to watch the conductor, he is like a metronome, but it is more difficult because he can change rhythms.

I wouldn't change Buffy for anything and I wouldn't change the course in which she has evolved but it is nice to be able to do something that is a little different.

For example, UNICEF works with governments to change legislation such as in India where a law was passed raising the age of compulsory school completion to keep children in school and away from the workplace for longer.

Great joy, especially after a sudden change of circumstances, is apt to be silent, and dwells rather in the heart than on the tongue.

I still feel that a movie has to attempt to say something - even if it fails miserably. But I've sort of given up on believing that I'm going to change the world with every film I choose to act in.

Don't knock the weather; nine-tenths of the people couldn't start a conversation if it didn't change once in a while.

You don't have to be the Dalai Lama to tell people that life's about change.

I knew that my staying up would not change the election result if I were defeated, while if elected I had a hard day ahead of me. So I thought a night's rest was best in any event.

It will always be a battle a day between those who want maximum change and those who want to maintain the status quo.

Being a father, well, I don't know if this is a change, but it makes me want to get out of here faster. Get off the clock. Just 'cause the baby is my reason for living, my reason for coming to work.

A liberal knows that the only certainty in this life is change but believes that the change can be directed toward a constructive end.

I was born not knowing and have had only a little time to change that here and there.

In their search for quality, people seem to be looking for permanency in a time of change.

The game has kept faith with the public, maintaining its old admission price for nearly thirty years while other forms of entertainment have doubled and tripled in price. And it will probably never change.

One day I actually took the list into the bathroom and I put it up against my face and looked in the mirror and I realized I had one of two choices, change the list or change myself.

But the real focus should be on people who are buying today because the base is so big it will take a long time for any change materialize on an overall basis.

Markets change, tastes change, so the companies and the individuals who choose to compete in those markets must change.

The psychological basis of the metropolitan type of individuality consists in the intensification of nervous stimulation which results from the swift and uninterrupted change of outer and inner stimuli.

Headteachers and governing bodies run schools and that won't change.

Using the power of decision gives you the capacity to get past any excuse to change any and every part of your life in an instant.

They said just keep doing my thing, don't try to change anything, which I won't.

Change can either challenge or threaten us. Your beliefs pave your way to success or block you.

My greatest challenge has been to change the mindset of people. Mindsets play strange tricks on us. We see things the way our minds have instructed our eyes to see.

Perhaps it's the people whose lives have taken sudden new twists - people who have learned to embrace the creative possibilities of change - who stand the best chance of penetrating life's mysteries.

It is not necessary to change. Survival is not mandatory.

Change is not a destination, just as hope is not a strategy.

Success, for me, is being able to provide information that will help to change someone's life positively.

I think we can be the very best place to start a business, to grow a business, to invent a new technology, to change the world, to change the country. But we've got a lot of work to deliver a new California to the people of California.

An organization's reason for being, like that of any organism, is to help the parts that are in relationship to each other, to be able to deal with change in the environment.