It's really kind of a challenge to keep coordinated with the two station crews that we'll be interacting with. And of course one of them launched quite some time before our mission.

In the Astronaut Office we're never totally out of training, we always keep our hand in it. But after five years, things have changed and so it's been good to get back into the flow and relearn a lot of things.

I did grow up with a really big interest in math and science; I liked it.

Our shuttle crew is four people, because we're going to transfer a crew up to station, so all the jobs are divided between four people rather than five or six people. So it's been busy.

Although I know a lot of the previous shuttle flights, in theory, had their tasks laid out; but there were still some changes that came along for them.

It's very important to know that we packed it right because it is a safety issue for coming home.

It is a very busy mission: every day has some major goals that we have to get through, but my experience before has been that at least in the evening, you kind of take a deep breath and look around where you are and have some downtime.

It's really kind of a challenge to keep coordinated with the two station crews that we'll be interacting with. And of course one of them launched quite some time before our mission.

A lot of these things will fly in later forms on the space station themselves, or a later form of that research will, once they kind of find out some of the basics from flying it on shuttle.

We still have a lot of international partner modules that need to get up there to make it truly the international structure that it will be, and that's highly important; we need to get to where the crew size is bigger.

I'll be the person using the shuttle robotic arm.

We're taking up some science experiments, some crystal growth things, we have a refrigerator that carries up some samples, new samples that go into the station, we bring the old ones home; we have a lot of clothing, we have a lot of food-U.S. and Russian food.

UF is Utilization Flight. That got put in the manifest quite some time ago.

We're on the same radius from the Earth, and then we start to swing around to where we're ahead of them on the velocity vector, so we come in relative to the station from this forward velocity position and dock on to the forward end of the Lab.

We launch when we're kind of in the same orbit that they are in terms of being matched up in inclination in space, and we're just in a little different altitude.

The training comes to us with the benefit of what has gone before.

It definitely helps to have been through the arm training flow before and to have used the arm on orbit, and it also gives me the confidence to know that our training facilities are really good, that when you get up there, you feel like you've been there.

We didn't use the shuttle robot arm before, so this has been a training flow to get ready for that.

I grew up watching a lot of the coverage of the early U.S. space program, all the way back starting with Mercury and then through Gemini and Apollo and of course going to the moon as the main part of the Apollo program.

It's really a good feeling to know that we put this up there, that it's working, that all these people's plans that worked so hard came together and things fit and we've got a real space station.

There's a lot of interest from the medical community on how things develop in microgravity, and the hope, later, that is expected to apply to what the changes are in humans as well.

As always, we prepare for all sorts of contingencies. And the first few days of the flight up until docking on Day 3 are all spent really in the rendezvous because we launch at a time that puts us in an optimal position to catch up to station.

Its very important to know that we packed it right because it is a safety issue for coming home.

Roosevelt's magic lay in one facet of his personality: He knew how to take the risk. No other man in public life I knew could so readily take the challenge of the new.

To do the Ozzfest again would be great. I'd like to finish with a final Sabbath album. You always feel that it is still a challenge.

People are not perfect... very often the relationships that are strongest are those where people have worked through big crises, but they've had to work through them. So the challenge to us is to work through that.

Every single book is a challenge.

Critics are sentinels in the grand army of letters, stationed at the corners of newspapers and reviews, to challenge every new author.

The lopsided attitudes of college professors pose a serious challenge to learning because students are so susceptible to becoming lopsided sheep.

I really enjoy comedy. It's a real challenge.

I had a hard time with that hockey. I hadn't grown up skating, so that was my biggest challenge. We worked on it and worked on it. But then when we first shot it, it was so hard for me.

The challenge is to practice politics as the art of making what appears to be impossible, possible.

Change can either challenge or threaten us. Your beliefs pave your way to success or block you.

My greatest challenge has been to change the mindset of people. Mindsets play strange tricks on us. We see things the way our minds have instructed our eyes to see.

I'd say that it's important for music to be there that gives you a challenge, that rearranges things in your head.

I like good stories. Quality products and character are what's important. Even if the script isn't that strong, if I challenge myself with a great character, I'll go for it.

I tend to arrive in the rehearsal process with very strongly developed ideas about what I want to do. But I don't like those ideas to be things that are not subject to change, or subject to development, or subject to challenge.

I'm not looking to set a standard... but, I believe I have offered a challenge to others with my work.

If you live a life of make-believe, your life isn't worth anything until you do something that does challenge your reality. And to me, sailing the open ocean is a real challenge, because it's life or death.

And, I'd never done Tennessee Williams, and I had done Broadway musicals, so it was a challenge.

When you remove the risk, you remove the challenge. When you remove the challenge, you wither on the vine.

After Land I wanted to continue exploring the theme but I needed a new challenge so turned to colour. I explored Bradford and produced a series of urban landscapes that I liked, but because Land had made such an impact on the general public my colour work wasn't reviewed.

The worlds I paint leave a lot to engage the imagination by hinting at what lies beyond the four edges of the painting. I think getting beyond the four edges of an opportunity or challenge is one of the basic skills you need in business.

For me, it's a bigger challenge, it's much harder to do and much more rewarding to do well, then just to think up stuff of your own, hit or miss, because you've got to see to it that you don't torpedo any of his punch lines.

This same habitual blindness to spiritual, substantive dimensions of every significant challenge continues to handicap Hollywood.

Every artist has to grow, and has to challenge themselves with a new form of expression.

The next challenge for Christianity is to remind Europeans that we are called to seek the truth.

Give yourself an even greater challenge than the one you are trying to master and you will develop the powers necessary to overcome the original difficulty.

The biggest challenge has been simulating a tornado with wind machines and dirt and debris. Right when you walk on the set, you feel the energy of a tornado. But the hardest thing is trying to get dialogue out in all of that.