What seems to be clear to me is that after the primary infection most of the cells die indirectly, but at the later stage, when the viral load is very high, the virus kills a lot of cells directly.

That is why it is so important not only to have excellent treatment but also to try to get back the immune defense, because there you have a natural defense that takes place everywhere.

Since most of the transmission is sexual transmission, you have a regional or local response to the virus.

We are working with a biotech company, Calypte, which has designed a urine test for the HIV antibody.

We don't know why, but there are some gradients of infection.

What perhaps should receive more attention is the effect of the treatment on the virus.

Our goal is not to completely eradicate the infection - that would be very difficult - but to produce a vaccine that will prevent not infection but disease. I think this is more possible.

They don't actually see the real world, where 95% of the people with HIV are not treated and are dying. And even though we have some blue sky now in our country, the sky could become cloudy again very soon.

The idea of the live-virus vaccine is to produce in a continuous way some viral antigens.

I've participated in meetings where there were concerns by ethical experts. There is no clear solution.

AIDS does not inevitably lead to death, especially if you suppress the co-factors that support the disease. It is very important to tell this to people who are infected.

Basic research is very useful, but it should be more geared toward application than it was before.

Psychological factors are critical in supporting immune function. If you suppress this psychological support by telling someone he's condemned to die, your words alone will have condemned him.

My proposal now is to test a vaccine first on people who have been infected, and if you show some efficacy at this level, you might be able to go further to study uninfected people in a population with a high rate of infection.

It's very difficult in our society. You cannot impose certain behavioral changes. Education can do it at the right time, probably by high school. After that it is too late.

AIDS win be our first priority, but in two years' time we don't know where AIDS research will stand, so we are also thinking of activity on other diseases.

I think we should put the same weight now on the co-factors as we have on HIV.

Another interesting field, which is my own, is cofactors, not only to the disease but also to transmission. I am still puzzled by the fact that you get more sexual transmission in some ethnic populations. One way to answer this is to look for genetic factors.

I am very puzzled by the fact that young people are getting infected again. They don't take precautions despite an enormous amount of information. It's like riding a race car at 200 kilometers an hour. Some people like the risk.

It's easier to learn things for life by the age of 12 and not the age of 18. This is just my guess.

What seems to be clear to me is that after the primary infection most of the cells die indirectly, but at the later stage, when the viral load is very high, the virus kills a lot of cells directly.

One could not have isolated this retrovirus without knowledge of other retroviruses, that's obvious. But I believe we have answered the criteria of isolation.

It's clear that prevention will never be sufficient. That's why we need a vaccine that will be safe.

The center will be fully operational in two years' time, but probably in the middle of the year we will have a temporary laboratory of 4,000 square feet.

They say a picture is worth a thousand words. In the nonprofit world, the right picture is worth tens of thousands of dollars. I use PhotoPad to sync our Samasource Flickr account to my iPad and slip it out of my purse at cocktail parties to tell our story.

Animals are my friends, and I don't eat my friends.

I think you've got to watch out for anybody in high school who says he wants to become an economist.

I've had a lot of fun watching my husband's wonderful career as a filmmaker unfold and all the interesting places we've been and people we've met. It's just been a really enjoyable ride.

Never stop. Never stop fighting. Never stop dreaming.

When a medium like games or comic books whips up such a rapture of enthusiasm, naturally we look for lessons we should be learning.

I think that when a film does its job, it poses questions rather than gives answers. It should act as a frustrating counselor who, at your bidding for advice, says, 'What do you think?' I think that's some of what the culture critic Greg Tate meant by art leaving a 'metaphysical stain.'

Life is like riding a bicycle. If you want to stay balanced youve got to keep moving forward.

If a black doctor discovers a cure for cancer, ain't no hospital going to lock him out.

You know what? Joy is the only guide. I'm going to have fun regardless.

Every small business will give you an entrepreneurial way of looking at things. I guarantee you that for every plant that closes, if you gave it to one small-business person in that community, he or she would find a way to make it work. The small-business attitude is you always find a way to make it work.

I took group lessons at a rink near my home. We first had to learn how to stand up on the ice wearing skates. Eventually we learned to move forward, but soon found out that it was not that easy to stop! So that was our next important lesson.

By the end of World War II, we were the most powerful and least damaged of the great nations. We also had most of the money. America's hegemony lasted exactly five years.

To show resentment at a reproach is to acknowledge that one may have deserved it.

We can create any sort of flavor on a printed image that we set our minds to.

I began writing in the 4th grade. As a matter of fact, I produced a play for the entire school. It was about Leif Ericson and the discovery of America.

I used to listen to Judy Garland all the time - I love Judy Garland and her music. But I started to realize that if you keep singing like that, singing songs of being victimized by love over and over and over again, it can't help but have a profound effect on your life.

I was brought up in a Christian home in Australia with a father who was very bold about his faith.

Feeling without judgment is a washy draught indeed; but judgment untempered by feeling is too bitter and husky a morsel for human deglutition.

If you are ambitious to talk well, you must be as much as possible in the society of well-bred, cultured people. If you seclude yourself, though you are a college graduate, you will be a poor converser.

I work in an industry where everyone is flawlessly beautiful, but I just want to be healthy.

Congress did the right thing with Ebola. They funded us to protect Americans and keep us safer.

Book clubs are the best thing that has happened to the world of publishing.

I'm very insecure. I'm human, just like anybody else.