My proposal now is to test a vaccine first on people who have been infected, and if you show some efficacy at this level, you might be able to go further to study uninfected people in a population with a high rate of infection.

That is why it is so important not only to have excellent treatment but also to try to get back the immune defense, because there you have a natural defense that takes place everywhere.

Since most of the transmission is sexual transmission, you have a regional or local response to the virus.

We are working with a biotech company, Calypte, which has designed a urine test for the HIV antibody.

We don't know why, but there are some gradients of infection.

What perhaps should receive more attention is the effect of the treatment on the virus.

Our goal is not to completely eradicate the infection - that would be very difficult - but to produce a vaccine that will prevent not infection but disease. I think this is more possible.

They don't actually see the real world, where 95% of the people with HIV are not treated and are dying. And even though we have some blue sky now in our country, the sky could become cloudy again very soon.

The idea of the live-virus vaccine is to produce in a continuous way some viral antigens.

I've participated in meetings where there were concerns by ethical experts. There is no clear solution.

AIDS does not inevitably lead to death, especially if you suppress the co-factors that support the disease. It is very important to tell this to people who are infected.

Basic research is very useful, but it should be more geared toward application than it was before.

Psychological factors are critical in supporting immune function. If you suppress this psychological support by telling someone he's condemned to die, your words alone will have condemned him.

My proposal now is to test a vaccine first on people who have been infected, and if you show some efficacy at this level, you might be able to go further to study uninfected people in a population with a high rate of infection.

It's very difficult in our society. You cannot impose certain behavioral changes. Education can do it at the right time, probably by high school. After that it is too late.

AIDS win be our first priority, but in two years' time we don't know where AIDS research will stand, so we are also thinking of activity on other diseases.

I think we should put the same weight now on the co-factors as we have on HIV.

Another interesting field, which is my own, is cofactors, not only to the disease but also to transmission. I am still puzzled by the fact that you get more sexual transmission in some ethnic populations. One way to answer this is to look for genetic factors.

I am very puzzled by the fact that young people are getting infected again. They don't take precautions despite an enormous amount of information. It's like riding a race car at 200 kilometers an hour. Some people like the risk.

It's easier to learn things for life by the age of 12 and not the age of 18. This is just my guess.

What seems to be clear to me is that after the primary infection most of the cells die indirectly, but at the later stage, when the viral load is very high, the virus kills a lot of cells directly.

One could not have isolated this retrovirus without knowledge of other retroviruses, that's obvious. But I believe we have answered the criteria of isolation.

It's clear that prevention will never be sufficient. That's why we need a vaccine that will be safe.

The center will be fully operational in two years' time, but probably in the middle of the year we will have a temporary laboratory of 4,000 square feet.

The principal rule of art is to please and to move. All the other rules were created to achieve this first one.

All enterprises that are entered into with indiscreet zeal may be pursued with great vigor at first, but are sure to collapse in the end.

Let me first state that I believe that marriage is a sacred union between one man and one woman.

Entropy theory is indeed a first attempt to deal with global form; but it has not been dealing with structure. All it says is that a large sum of elements may have properties not found in a smaller sample of them.

There is no need to do any housework at all. After the first four years the dirt doesn't get any worse.

The avantgarde are people who don't exactly know where they want to go, but are the first to get there.

I never taste the wine first in restaurants, I just ask the waiter to pour.

After the first miscarriage, I tried to take the attitude that it was my body's way of telling me that this pregnancy wasn't meant to be.

Before and during the first phase of the war his administration repeatedly maligned the UN but now, that Iraq has turned into a quagmire, it is asking the UN for help.

You look at the whole Human Rights questions, I happened to be there at just the right time when the country was awakening - this goes to the first question you asked - the whole country was awakening to a hundred years of injustice that hadn't been resolved yet.

So, first you have to be able to play with a metronome. Then you take your freedom. If you play in an orchestra, you got to watch the conductor, he is like a metronome, but it is more difficult because he can change rhythms.

My first figure was a SLAYER eagle. And the dragons and the tribals are all I have got.

We're parents first, and once you have kids, everybody knows that you have priority lists. Number one is your family and everything else just kind of finds its place.

Everything has to be pulling weight in a short story for it to be really of the first order.

But in the first Gulf war the United Kingdom was not under any threat from Iraq, and is still less so in the second one. Then there is no justification for obstructing freedom of information, particularly as nations have a right to know what their soldiers are being used for.

I sort of understood that when I first started: that you shouldn't repeat a success. Very often you're going to, and maybe the first time you do, it works. And you love it. But then you're trapped.

Working-class Americans have waited too long, close to a decade in fact, for an increase in the minimum wage. This has been the second longest period without a pay raise since the Federal minimum wage law was first enacted in 1938.

The first thing you do when you get out to center field is put up your finger and check the wind chill factor.

Christians must be Jews. The truth of what we believe depends on the truth of Judaism, depends on the first covenant.

The international proletariat first appeared on the scene in the early Thirties of the nineteenth century, and its first great action was the French Revolution of 1848.

Success requires first expending ten units of effort to produce one unit of results. Your momentum will then produce ten units of results with each unit of effort.

I want to be the first lady to land a quadruple jump in competition. As I grow older, I know that my skating style will develop and mature.

I bought my first camera in Seattle, Washington. Only paid about seven dollars and fifty cents for it.

Let the one among you who is without sin be the first to cast a stone.

Obviously I faced the possibility of not returning when first I considered going. Once faced and settled there really wasn't any good reason to refer to it.