We don't know why, but there are some gradients of infection.

That is why it is so important not only to have excellent treatment but also to try to get back the immune defense, because there you have a natural defense that takes place everywhere.

Since most of the transmission is sexual transmission, you have a regional or local response to the virus.

We are working with a biotech company, Calypte, which has designed a urine test for the HIV antibody.

We don't know why, but there are some gradients of infection.

What perhaps should receive more attention is the effect of the treatment on the virus.

Our goal is not to completely eradicate the infection - that would be very difficult - but to produce a vaccine that will prevent not infection but disease. I think this is more possible.

They don't actually see the real world, where 95% of the people with HIV are not treated and are dying. And even though we have some blue sky now in our country, the sky could become cloudy again very soon.

The idea of the live-virus vaccine is to produce in a continuous way some viral antigens.

I've participated in meetings where there were concerns by ethical experts. There is no clear solution.

AIDS does not inevitably lead to death, especially if you suppress the co-factors that support the disease. It is very important to tell this to people who are infected.

Basic research is very useful, but it should be more geared toward application than it was before.

Psychological factors are critical in supporting immune function. If you suppress this psychological support by telling someone he's condemned to die, your words alone will have condemned him.

My proposal now is to test a vaccine first on people who have been infected, and if you show some efficacy at this level, you might be able to go further to study uninfected people in a population with a high rate of infection.

It's very difficult in our society. You cannot impose certain behavioral changes. Education can do it at the right time, probably by high school. After that it is too late.

AIDS win be our first priority, but in two years' time we don't know where AIDS research will stand, so we are also thinking of activity on other diseases.

I think we should put the same weight now on the co-factors as we have on HIV.

Another interesting field, which is my own, is cofactors, not only to the disease but also to transmission. I am still puzzled by the fact that you get more sexual transmission in some ethnic populations. One way to answer this is to look for genetic factors.

I am very puzzled by the fact that young people are getting infected again. They don't take precautions despite an enormous amount of information. It's like riding a race car at 200 kilometers an hour. Some people like the risk.

It's easier to learn things for life by the age of 12 and not the age of 18. This is just my guess.

What seems to be clear to me is that after the primary infection most of the cells die indirectly, but at the later stage, when the viral load is very high, the virus kills a lot of cells directly.

One could not have isolated this retrovirus without knowledge of other retroviruses, that's obvious. But I believe we have answered the criteria of isolation.

It's clear that prevention will never be sufficient. That's why we need a vaccine that will be safe.

The center will be fully operational in two years' time, but probably in the middle of the year we will have a temporary laboratory of 4,000 square feet.

The special relationship between twins is that, if there's anyone else in the world that's going to get or be the confidant that you need, it's an identical twin.

I've told several writers this, and, again, I get back to it, but if you want to make God smile, tell him your plans.

The sting of losing is bad.

It's that way all the way down the line. I've got a boy coaching college ball and another son coaching high school. All the way down to summer leagues, all the way down to kids who are 14 years old. All those teams have a closer.

My responsibility is, I'm always trying to look for new people of color or even artistic people who need a chance.

I thought of computers as very low class. I thought of myself as a pure mathematician and was interested in partial differential equations and topology and things like that.

I sort of tried to get a basketball scholarship out of high school, but that didn't happen. Then I started working for UPS, and that paid for tuition for school. I moved to a bigger town, Louisville. I did it for a year. I had to work the graveyard shift. And then you get off at eight for classes, so that sucked. Then I dropped out.

Being unique is never easy and often by the time culture catches up with you there are only a few people who notice.

As you get older, the days have gone, and the years have gone, and it's 'whoosh!'

I love a smart, educated woman.

The company, Tiffany Studios, ended up in bankruptcy in 1930 - early '30s.

Patriotism is a love of country. If you love your country, you should love your countrymen and women. It doesn't mean you always agree with them or even like them. It is understanding that we have interwoven destiny.

A wedding is for daughters and fathers. The mothers all dress up trying to look like young women. But a wedding is for a father and daughter. They stop being married to each other on that day.

The beauty of standing up for your rights is others see you standing and stand up as well.

There certainly is a good 'Tex Mex' restaurant very close to our office. My office is around 100 yards from it. I call it Tex Mex because every couple of years it's changed hands and changed name, I'm not exactly sure why!

My mom and I were super tight. I think she really wanted me to be an artist, you know? She used to like to tell people she wanted to be Beethoven's mother. That was her thing. She wanted to be the mother of this person.

I recently saw the movie about Ray Charles, and there's a scene where he falls down and the mother doesn't help him. She says, I don't want anyone to treat you like a cripple. I've fallen down before, and Molly will say, get up and just go.

The Spending Control Act. It would recreate President Reagan's grace commission to have a bipartisan commission on how we reduce spending.

The difference between technology and slavery is that slaves are fully aware that they are not free.

One of the things I love about our source text as Christians, the Bible, is that it teaches us not to avoid conflict. And it teaches us that before the fall of man, in Paradise, there was conflict. God wants conflict to be a part of your life.

The earth only has so much bounty to offer and inventing ever larger and more notional prices for that bounty does not change its real value.

It's easy to show terrible people's behavior on screen, and we all just kind of nod and go, 'Isn't that terrible.' It's more interesting when you can show terrible behavior in the interest of something good.

No matter how brilliant your mind or strategy, if you're playing a solo game, you'll always lose out to a team.

We owe respect to the living; to the dead we owe only truth.