In teaching, I wanted to offer a general pharmacology course based on chemical principles, biochemical classification and mathematical modelling. In the event I achieved neither of my ambitions.

My father, a mining engineer and colliery manager, gave his brood many advantages not least of which, for me, was his love of singing which gave music a central place in our lives.

All I ever promised was that I was sure I could develop a new pharmacological agent which might answer a physiological question. Any utility would be implicit in that answer.

I met Hilary Vaughan at a Student Ball in 1944 and we married in the summer of 1946, as soon as I graduated.

In teaching, I wanted to offer a general pharmacology course based on chemical principles, biochemical classification and mathematical modelling. In the event I achieved neither of my ambitions.

The Wellcome Foundation offered me the chance to establish a small academic research unit, modestly funded, but with total independence. The real opportunity, however, came from King's College, London.

During my six years with them Dr Garnet Davey (subsequently Research Director) constantly supported me and, I have no doubt, fought many battles on my behalf to keep the initially controversial programme going.

Half-jokingly, I asked what was wrong with me. So we made a deal: I would run his biological research provided I had a free hand to run my new project.

Apart from two periods of intense study, of music between the ages of 12 and 14 and of mathematics between the ages of 14 and 16, I coasted, daydreaming, through most of my school years.

The outcome, the fourth in an issue of five boys born into a staunch Baptist home, meant that from the beginning I was taught to be respectful of others no less than myself, influencing ever since both my political and administrative attitudes.

I had found myself a new mission - and once more my recurring dilemma between corporate commercial needs and personal scientific ambitions was solved unexpectedly.

We paid off our debts, we learned some, made friends and returned in 1950 with a larger view of life. I had, however, no home, no income of any kind and no prospects whatsoever.

I did help to set up an undergraduate course in medicinal chemistry and made progress in modelling and analysing pharmacological activity at the tissue level, my new passion.

I frankly don't care if you agree with my stand on abortion. I take that stand because no other stand is consistent with decent principles, and no other standard is consistent with the will of God.

We should have a State in which we could live and breathe as free men and which we could develop according to our own lights and culture and where principles of Islamic social justice could find free play.

This means that to entrust to science - or to deliberate control according to scientific principles - more than scientific method can achieve may have deplorable effects.

The 'morality of compromise' sounds contradictory. Compromise is usually a sign of weakness, or an admission of defeat. Strong men don't compromise, it is said, and principles should never be compromised.

Our purpose is simply to ask how theological principles can be shown to have usable secular analogues that throw light upon the nature of language.

If you look to lead, invest at least 40% of your time managing yourself - your ethics, character, principles, purpose, motivation, and conduct. Invest at least 30% managing those with authority over you, and 15% managing your peers.

Almost the only persons who may be said to comprehend even approximately the significance, principles, and purposes of Socialism are the chief leaders of the extreme wings of the Socialistic forces, and perhaps a few of the money kings themselves.

Native Americans are the original inhabitants of the land that now constitutes the United States. They have helped develop the fundamental principles of freedom of speech and separation of powers that form the foundation of the United States Government.

Nature is my manifestation of God. I go to nature every day for inspiration in the day's work. I follow in building the principles which nature has used in its domain.

Politics is about winning. If you don't win, you don't get to put your principles into practice. Therefore, find a way to win, or sit the battle out.

Tony Blair has turned his back on the principles he claimed he believed in before he stood shoulder-to-shoulder with George W. Bush. He was an entirely different kind of leader.

Apart from a few simple principles, the sound and rhythm of English prose seem to me matters where both writers and readers should trust not so much to rules as to their ears.

Policies are many, Principles are few, Policies will change, Principles never do.

My objection to Liberalism is this that it is the introduction into the practical business of life of the highest kind namely, politics of philosophical ideas instead of political principles.

Change your opinions, keep to your principles; change your leaves, keep intact your roots.

The impression I have of Justice Warren is that he was looking for the just result in a case regardless of fixed dogma or principles and I like to think that I'm in that mold.

After a long, impartial enquiry of the truth, and after much and earnest calling upon God, to give unto me the spirit and revelation in the knowledge of Him, I find myself obliged, both by the principles of reason and Scripture, to embrace the opinion I now hold forth.

When a battle for suffrage is conducted, it should only be conducted according to socialist principles, and therefore with the demand of universal suffrage for women and men.

The spirit in which the offer was made must of necessity contribute to improving and alleviating the situation of the Jewish people without our renouncing one iota of the great principles upon which our movement is based.

Just as we outgrow a pair of trousers, we outgrow acquaintances, libraries, principles, etc., at times before they're worn out and times - and this is the worst of all - before we have new ones.

My guiding principles in life are to be honest, genuine, thoughtful and caring.

But the more an organization succeeds and prospers, the more it is likely to be diverted from its original ideals, principles and purposes.

Entertaining these opinions of the course to be pursued, I beg of gentlemen to look at the question, as I have done, in a calm review of facts and of principles.

When I had made more money than I needed for myself and my family, I set up a foundation to promote the values and principles of a free and open society.

It is always easier to fight for one's principles than to live up to them.

Be thou incapable of change in that which is right, and men will rely upon thee. Establish unto thyself principles of action; and see that thou ever act according to them. First know that thy principles are just, and then be thou.

Thus self-love as one part of human nature, and the several particular principles as the other part, are, themselves, their objects and ends, stated and shown.

A man is usually more careful of his money than of his principles.

In the span of my own lifetime I observed such wondrous progress in plant evolution that I look forward optimistically to a healthy, happy world as soon as its children are taught the principles of simple and rational living.

The principles of justice are chosen behind a veil of ignorance.

Every science has for its basis a system of principles as fixed and unalterable as those by which the universe is regulated and governed. Man cannot make principles; he can only discover them.

I many no longer depend on pleasant impulses to bring me before the Lord. I must rather response to principles I know to be right, whether I feel them to be enjoyable or not.

But there's no reason why we should abdicate our foundational principles because certain groups don't believe in them. You know, no majority should surrender its deeply held beliefs to those who don't believe in anything.

Our strategic dialogue with China can both protect American interests and uphold our principles, provided we are honest about our differences on human rights and other issues and provided we use a mix of targeted incentives and sanctions to narrow these differences.

At the descriptive level, certainly, you would expect different cultures to develop different sorts of ethics and obviously they have; that doesn't mean that you can't think of overarching ethical principles you would want people to follow in all kinds of places.

Just because people are in authority, if it doesn't seem right, don't do it. If it violates your own principles, don't do it.