The outcome, the fourth in an issue of five boys born into a staunch Baptist home, meant that from the beginning I was taught to be respectful of others no less than myself, influencing ever since both my political and administrative attitudes.

My father, a mining engineer and colliery manager, gave his brood many advantages not least of which, for me, was his love of singing which gave music a central place in our lives.

All I ever promised was that I was sure I could develop a new pharmacological agent which might answer a physiological question. Any utility would be implicit in that answer.

I met Hilary Vaughan at a Student Ball in 1944 and we married in the summer of 1946, as soon as I graduated.

In teaching, I wanted to offer a general pharmacology course based on chemical principles, biochemical classification and mathematical modelling. In the event I achieved neither of my ambitions.

The Wellcome Foundation offered me the chance to establish a small academic research unit, modestly funded, but with total independence. The real opportunity, however, came from King's College, London.

During my six years with them Dr Garnet Davey (subsequently Research Director) constantly supported me and, I have no doubt, fought many battles on my behalf to keep the initially controversial programme going.

Half-jokingly, I asked what was wrong with me. So we made a deal: I would run his biological research provided I had a free hand to run my new project.

Apart from two periods of intense study, of music between the ages of 12 and 14 and of mathematics between the ages of 14 and 16, I coasted, daydreaming, through most of my school years.

The outcome, the fourth in an issue of five boys born into a staunch Baptist home, meant that from the beginning I was taught to be respectful of others no less than myself, influencing ever since both my political and administrative attitudes.

I had found myself a new mission - and once more my recurring dilemma between corporate commercial needs and personal scientific ambitions was solved unexpectedly.

We paid off our debts, we learned some, made friends and returned in 1950 with a larger view of life. I had, however, no home, no income of any kind and no prospects whatsoever.

I did help to set up an undergraduate course in medicinal chemistry and made progress in modelling and analysing pharmacological activity at the tissue level, my new passion.

From the beginning, the series has been story driven - I began with a story idea - but research feeds it.

I don't write drafts. I write from the beginning to the end, and when it's finished, it's done.

Since the beginning, I always loved the game. When you grow up in Montreal, one day you want to be a professional hockey player. When I was six or seven, I knew that was what I wanted.

Before beginning, plan carefully.

Every new beginning comes from some other beginning's end.

The people who voted for President Obama are just beginning to wake up to exactly what they brought in. The 'change' they envisioned is not the 'change' they have gotten.

Religion has caused more harm than any other idea since the beginning of time. There's nothing good I can say about it. People use it as a crutch.

And that's how I start myself. I usually go back a couple of pages, maybe to the beginning of the chapter, and I start reading. And as I'm reading, I'm tweaking - putting in a different word, changing the syntax, putting that clause over there, you know that sort of thing.

In the beginning it was all black and white.

A palindrome is a word or pattern that instead of developing in different directions it folds in on itself so that the beginning and end mirror each other, that they are the same.

Learning is the beginning of wealth. Learning is the beginning of health. Learning is the beginning of spirituality. Searching and learning is where the miracle process all begins.

At the beginning of 1955 only about 60 percent of American homes had TVs.

Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning.

Most musicians count at the beginning, and never count and talk to their musicians after that. They only talk to them at the end of the song. But I would count with them and talk.

What you really remember at the beginning was that you have to throw a budget together. We made some terrible mistakes at the beginning in my own budget that took us at least a year to catch up on.

There is a spirit and a need and a man at the beginning of every great human advance. Every one of these must be right for that particular moment of history, or nothing happens.

I am pleased to see that information campaigns, such as the America's WETLAND effort, are getting the message out, and people are beginning to realize that wetlands loss in Louisiana affects us all.

I started working on trying to sound like June from the very beginning.

The end comes when we no longer talk with ourselves. It is the end of genuine thinking and the beginning of the final loneliness.

Even though the future seems far away, it is actually beginning right now.

It is a curious sensation: the sort of pain that goes mercifully beyond our powers of feeling. When your heart is broken, your boats are burned: nothing matters any more. It is the end of happiness and the beginning of peace.

The American Revolution was a beginning, not a consummation.

All great deeds and all great thoughts have a ridiculous beginning. Great works are often born on a street corner or in a restaurant's revolving door.

The beginning of 1856 found me teaching in the family of a planter named Bryan, residing in Prince George County, Md., some fifteen or twenty miles from Washington.

I did all the work at the beginning up until the point where I couldn't handle the increasingly heavy art production burden alone. I needed, and got, assistance.

Art at its most significant is a Distant Early Warning System that can always be relied on to tell the old culture what is beginning to happen to it.

You know, in the beginning when your first payroll comes up and you have to borrow money to meet the payroll, you lose sleep the night before, and you say to yourself real fast, 'Well, maybe I should keep working a couple more years. It's sobering.

I think I realized it was an art form at the beginning, but it took me a really long time before I was able to view what I was performing myself as an art form.

In the beginning I had a real work problem. Every time I had job I had to convince the immigration authorities I was the only man for that job and get a special work permit until I went under contract to MGM.

It's interesting that instead of having to get tighter and more restricted for a collaboration, strangely enough, from the beginning, we've actually been more confident that we could handle this.

No cause is left but the most ancient of all, the one, in fact, that from the beginning of our history has determined the very existence of politics, the cause of freedom versus tyranny.

At the beginning, it was me, Run and D, but D's voice is messed up.

It's that event that's the beginning of the avalanche of this play. The first loose rock.

Through the wholesale destruction of the representatives of a class that from the beginning of history had been the directing and creative force in civilization, a process began which was almost mechanical.

I caution against beginning or ending a quotation with ellipses.

I used to tremble from nerves so badly that the only way I could hold my head steady was to lower my chin practically to my chest and look up at Bogie. That was the beginning of The Look.