Grissom is pretty asexual. He's not that interested in anything other than work - except for Lady Heather. She's the closest to getting his heart of anyone.
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Grissom comes from a place where we know he had a deaf mother, he was raised in a silent household, on some level, had a father who potentially was not around and he learned what he knew by himself in the back yard, with bugs and animals. He's not comfortable being a supervisor and that's his problem.